The latest major change to the Microsoft Anti-Spyware app, now called Windows Defender, has turned the tool into an invaluable one on my machine. So, MS has a real fix: wipe your drive, and reinstall. According to the story on eWeek, Mike Danseglio, program manager in the Security Solutions group at Microsoft. The choice quote from Mike is, "When you are dealing with rootkits and some advanced spyware programs, the only solution is to rebuild from scratch. In some cases, there really is no way to recover without nuking the systems from orbit." Mike goes on to explain some malware is just "way too hard" to remove, thus requiring a total wipe and reinstall. They had to do this with a certain unnamed government branch, wiping and restoring 2,000 machines.